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American Society of Microbiology ABMM Web-Based Practice Exam - Reliable Online Self-Assessment Test

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American Society of Microbiology ABMM Sample Questions (Q113-Q118):

NEW QUESTION # 113
A patient with HIV infection and a low CD4+ T-cell count presents with fever, weight loss, and cough. Chest X-ray shows diffuse interstitial infiltrates. Sputum induction reveals oval yeast cells with narrow-based budding. The MOST likely diagnosis is:

A. Cryptococcosis
B. Pneumocystis pneumonia
C. Histoplasmosis
D. Tuberculosis

Answer: C

NEW QUESTION # 114
A patient undergoing chemotherapy for leukemia develops a severe pneumonia. Bronchoalveolar lavage fluid is examined, revealing numerous cysts containing crescent-shaped structures upon silver staining. The patient's CD4+ T-cell count is significantly low. The MOST likely diagnosis is infection with:

A. Histoplasma capsulatum
B. Blastomyces dermatitidis
C. Pneumocystis jirovecii
D. Coccidioides immitis

Answer: C

NEW QUESTION # 115
During a community outbreak of influenza, a public health laboratory performs rapid antigen testing on nasopharyngeal swabs. A test for influenza A is positive, but the influenza B test is negative. Subsequently, RT-PCR is performed on the same sample, and it is negative for both influenza A and B viral RNA. The MOST likely explanation for this discordant result is:

A. The rapid antigen test has low sensitivity, resulting in a false positive.
B. The rapid antigen test yielded a false positive result, and the RT-PCR was a true negative.
C. The patient was infected with a novel influenza strain not detected by either assay.
D. The RT-PCR assay has a high limit of detection, missing a low viral load.

Answer: B

NEW QUESTION # 116
A research team is investigating the mechanism of bacterial resistance to a novel fluoroquinolone antibiotic.
They isolate a resistant strain of Escherichia coli from a patient with a urinary tract infection. Genetic analysis of this strain reveals a point mutation in the gyrA gene. This mutation MOST likely results in:

A. Alteration of the DNA gyrase enzyme, reducing its affinity for the fluoroquinolone.
B. Modification of the ribosomal target site, preventing antibiotic binding.
C. Production of an enzyme that inactivates the fluoroquinolone molecule.
D. Increased expression of efflux pumps that actively transport the antibiotic out of the cell.

Answer: A

NEW QUESTION # 117
A traveler returning from Southeast Asia presents with fever, headache, and a maculopapular rash that started on the trunk and spread to the extremities, including the palms and soles. Serological testing is positive for Orientia tsutsugamushi. The vector responsible for transmitting this organism is a:

A. Mosquito
B. Mite (chigger)
C. Tick
D. Flea

Answer: B

NEW QUESTION # 118
......

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